- Community (198)
- Uncategorized (70)
- Friends and Family (38)
- Newly Diagnosed (52)
- Side Effects (20)
- Coping with Cancer (59)
- Survivor Stories (54)
This post send by kim
Please read more about fasting prior to chemotherapy drugs that usually make you sick with nausea and vomiting and are followed by other things such as mouth sores or mucousitis. This worked for my son who without fasting had Emend and steroids and zofran and ativan but still threw up 5-8/day before fasting. With fasting he threw up ZERO!
HERE IS ONE ARTICLE:
Fasting can protect cells from stress and damage, such as oxidation or radiation, and has been found to protect healthy cells from chemotherapy. But can the practice also help fight cancer?
There is now evidence to support this idea, from research on cancer models of yeast and tumor-ridden mice, published today (February 8) in Science Translational Medicine. Starved organisms survived longer when treated with chemotherapy than those on a normal diet, and healthy cells were less likely to sustain damage.
“This ability to think about adding fasting in combination with chemotherapy is obviously exciting, and it definitely adds something to the arsenal of what we can do,” said Trudy Oliver, who researches cancer resistance at the University of Utah but was not involved in the study.
Chemotherapy works by attacking rapidly dividing cells, a hallmark of cancer. Previous studies suggested that fasting before treatment could help protect healthy cells by slowing their growth even further. But one question loomed in researchers’ minds: “What happens to the cancer cells?” said study co-author Valter Longo, who studies the molecular mechanisms of aging at the University of Southern California. If fasting slowed down cancer cell growth enough to reduce the effectiveness of chemotherapy, “this would be a problem.”
Initial results in cancer-mimic yeast and cancerous mammalian cell lines provided Longo with evidence that starvation slows cancer growth and also enhances healthy cell survival when faced with chemotherapy. These results encouraged Longo to move into mouse models. “If it doesn’t change from yeast to mammalian cells, we figured that it is something so conserved and fundamental it’s going to apply to humans too,” he said.
Longo\’s team studied a variety of mouse models. Mice were injected with both human and mouse cancers, including breast cancer, melanoma, and the nervous system cancer neuroblastoma, among others. The researchers also tested several types of chemotherapy drugs. And each experimental combination was subjected to three treatments: just fasting, by being given only water for 48–60 hours prior to treatment, just chemotherapy, or fasting and chemo together.
Results varied by cancer type and treatment, but overall the combination of fasting and chemotherapy reduced cancer growth significantly, and starved mice survived far longer than their non-starved counterparts. For example, melanoma metastasis was found in 40 percent of mice given just chemotherapy, 20 percent under starving conditions alone, and 10 percent of mice that underwent chemotherapy and fasting.
“The surprising part was that, for several cancers including breast cancer, fasting cycles alone were as good as chemotherapy,” said Longo. “We expected some delay but not an equivalent effect.”
Gene expression assays and molecular analyses suggested that, in cancer cells but not healthy cells, fasting and chemo together induce a 20-fold increase in DNA damage, an increase in oxidative stress, and higher incidence of cleaved caspase 3, a protein that induces cell death.
Longo hypothesizes that, while normal cells are well-equipped to deal with starvation by slowing their metabolism to just essential activities, cancer cells “became better at growing and growing and worse at adapting to new conditions.” When cancerous cells are faced with a hostile environment, such as starvation, they become weak and shut down. “And, when they become weak, chemotherapy has an easier time,” he added. However, he emphasized, this is still a hypothesis.
While Oliver finds the results “provocative,” she would like to see the molecular mechanisms fleshed out more, especially because the pathway is so “counter-intuitive.”
“You might think it would work the other way: that chemo is not going to work as well anymore if you slow down cancer growth,” she said. Future studies should try to elucidate the mechanism and study the phenomenon in more in vivo cancer models to “show us the effect directly on proliferation as a result of that fasting,” she added.
There are already three clinical trials— one of which is at the University of Southern California—underway studying the combination of fasting and chemotherapy in human patients.
Longo suspects that the human equivalent of 48–60 hours of mouse fasting is about five days, based on glucose and growth factor concentrations. Five days is a long time, noted Oliver, and fasting “may be rough for cancer patients who are already going through a lot.” But uncovering the mechanism could lead to better solution, she added.
“It might be that people don’t need to starve to do the same thing, if they can take a new drug with chemotherapy that mimics starvation but is not as painful as starvation,” Oliver said. “That underscores the importance of finding the mechanism.”
C. Lee et al., \"Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy,\" Science Translational Medicine, doi:10.1126/scitranslmed.3003293, 2012
This post send by Johnathon Yeager
My name is Johnathon, and I was diagnosed with stage 4 neuroblastoma cancer on 07/07/07 at the age of 14. Since then I have done almost every treatment out there, and at the age of 20 im still fighting, having relasped 3 times. It certainly has been a rough journey, one that has defined my life and altered the person i am today. I am grateful to be alive each day, as I thank God and the ones around me with all there help. Cancer sucks, and i wish i did not have it, but everyone has there own struggles and there own way to persevere. This website is a great way to connect with other individuals and Im glad there are others out there who can understand how hard this journey can be. If anyone out there needs help, advice, or just wants a friend to talk to, maybe share some battle stories and count how many surgery scars we have then please message me! My email is email@example.com Also anyone in the upper midwest specifically north dakota or minnesota, it would be great to fight together! Cancer sucks and i wish it upon no one. just stay strong and fight on! Positivity is key to beating cancer and becoming a survivor. Past survivors are truely an inspiration to me and i hope i can inspire others to stay happy. facebook me as well! Johnathon Yeager be my name! See yall later and keep kicking butt!
This post send by Johnathon Yeager
I was diagnosed with stage 4 neuroblastoma cancer at the age of 14. No one deserves to go through such horrible things, but it happens. I have done every possible treatment it can think of: chemo, radiation, experimental, MIBG therapy, bone marrow transplant, immunotherapy.. Whatever! I relapsed 3 times am still continuing to fight it at the age of 20! For those of you put there in the same boat, just stay strong and continue to fight with your head held high. It may sound easier said than done, but it\’s the only way to kick cancer\’s A**! Positivity is key. If anyone wants a friend to talk to or have any question my email is firstname.lastname@example.org! Especially for those of you in the upper Midwest! North Dakota and Minnesota! Stay strong and always try to smile keep fighting.
This post send by Jade Olson
My name is Jade Olson, I am 16 years old and I was diagnosed with leukemia in April 2013. I had to move 4 hours away from home to get my treatments here in Phoenix and i am having a hard time relating to people who arent dealing with the same things i am… if anyone is in this area, or anywhere really, who are battling cancer i would love to connect with you and chat about things we have to deal with that no one else understands. My facebook is https://www.facebook.com/jade.olson.12382 hit me up on there if you want someone to talk to.
This post send by Rhiannon Deamer
I\\\’ve recently been diagnosed with type AML Leukaemia and want to get to know other people in the same situation as me☺
This post send by Savannah
Okay, so they switched my chemo to a regimen called folfox. Which is commonly used for colon cancer but in this case is being used for my liver cancer. Since I began this drug it has been soooo much worse than the other stuff I was on. I am having side effects which include the normal (fatigue, nausea, decreased appitite etc.) But now I also have new side effects which include painful tingling in my hands and feet when anything cold touches them, stinging in my throat when drinking anything cold, and more hair loss. These symptoms are normal for my chemo from what I am told. But my problem is that I am having certain side effects that my doctors are not able to explain. This includes increased urination sometimes and other times urinating without knowing it, extreme burning in my throat and chest whenever I eat anything (cold or hot) And sometimes when the burning occurs I feel as if I cant breath. Which is extremely terrifying. I would just like to know if anyone has had these symptoms on folfox or on any other chemo, and what I should do about it. Because my health is slowly getting worse when chemo is suppose to be curing my cancer. I know that chemo takes a huge toll on ur body but still… Also my doctors believe I may be contracting diabetes on this chemo, has this happened to anyone also? Any info or advice is greatly appreciated I am just starting to get scared and I am sorry to those of you who feel this is TMI but I just need to know if anyone else has experienced this. Thanks
This post send by
This post send by Karen Rice
When I was diagnosed with Breast cancer a few years back, I reacted like most who receive a cancer diagnose; first thing came to mind was a “death sentence”. However, I found out later that it was truly “an awakening” for me; even after being diagnosed with colon cancer a few years later. I began questioning God, why would you do this to me? What had I done in life so bad to have this placed upon me? But instead of bemoaning my fate, I decided to look for the positive side of it. There has to be a reason for it all.
I also realized that I was about to face a new beginning, new hope, do and see more with a whole new prospective on life. When I think of the “gift of life” that was given to me, I know that I will develop and gain strength from all my experiences. Even with the complications I now have to live with, and all the struggles I\\\’ve dealt with my entire life, I still feel truly blessed. For a while, I wasn\\\’t happy with the way I looked after my surgery and the pain I had to endure each day, but I decided to snap out of it. I thought about the individuals that are no longer among us. I also realized that there will always be someone worse off than I am. I reminded myself, that I “still have my life” and who am I to complain.
One day I experienced something of a miracle and felt the compulsion to write it down. I turn that experience into a poem and I called it “Peace”. Writing has become therapy for me. I took that poem, along with many others I had composed during my breast cancer period and placed them into book form. I was blessed enough to have that book published and it\\\’s titled “True Simple Poems of Life, Faith and Survival”. I\\\’m hoping that anyone who has the opportunity to read my poems, get out of them, what I placed in all of them. My poems are from the heart, as real as any could ever be. With the words and phrases of each poem of statement, I wish to make a positive impact on someone who\\\’s ill or otherwise, where they could develop the strength to embrace life in a whole new way. I never anticipated becoming a writer, I just became one. I truly believe when you survive a horrific tragedy or a horrible disease as cancer, it\\\’s for a reason, “you have a purpose” and I want to live to find find out exactly what that is for me.
I recently had another inspirational book published, titled “If Only I Could Fly, said Mattie-bee” and I\\\’m working on my third. See, that\\\’s what I\\\’m all about now, inspiration. I would have never become a writer, producing inspirational poems and stories, if I had not gone through all that I did. I\\\’m a true example that you can survive cancer not once, but twice, providing you catch it in time, have faith and allow that faith to direct your path. I\\\’ve not saying all will be easy, but you must believe. This is what my experiences with cancer made of me, a true believer!
Karen Rice/x2 Cancer Survivor
This post send by Kimmy
I am a first year Radiation Therapy student in university this year. I am from South Africa.
I have had a lot of experience with cancer patients in my life, with family and friends, this is what has driven me to entire the field.
I\\\’ve had experience with skin cancer patients, leukemia, breast cancer, cervical cancers.. and I have formed bonds with my patients and been a friend.
I was born to help. Let me know how I can.
I can\\\’t present you with any answers or solutions.
But I can be a friend. You won\\\’t judge you..I will listen to you..and be there for you the best I can.
this is my email. Feel free to contact me.
This post send by Ivylin Cordova
Hi everyone my name is ivylin Cordova I\\\’m a cancer survivor and I have PTSD from it I was 13 when I had Rhabdomyosarcoma I was really scared when I found out I didn\\\’t know what to do I had really bad depression none of the people I went to middle school with know I had cancer only one knew my best friend I told her the day I found out she started to cry hard I cried hard to I couldn\\\’t breath for a moment I told her ill be ok ill be fine she said ok she asked me if anyone else knew I said only my family and you that\\\’s it and I was so angry,sad I didn\\\’t want to believe it had it a month after I turned 13 I wanted to cry I had it in my uterus I couldn\\\’t stop bleeding for 6 months I knew something was wrong so did my mom she told the doctors what was wrong with me they said it was regular teenage stuff I didn\\\’t believe it but I\\\’m 2 years cancer free I\\\’m 15 now I\\\’m great I have a beautiful girlfriend and I\\\’m proud to be bisexual ☺ CANCER SUCKS!!!!